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Literature summary extracted from
- Potent inhibition of ribonuclease A by oligo(vinylsulfonic acid) (2003), J. Biol. Chem., 278, 20934-20938.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.6.1.18 | oligo(vinylsulfonic acid) | potent competitive inhibitor making nearly 8 favorable Coulombic interactions with the enzyme. Oligo(vinylsulfonic acid) is inexpensive and extremely stable. Accoringly oligo(vinylsulfonic acid) has the potential to be useful prophylactic in many chemical, biochemical, and biotechnical experiments involving RNA | Bos taurus |  |
| 4.6.1.18 | poly(vinylsulfonic acid) | - |
Bos taurus | |
| 4.6.1.18 | poly(vinylsulfuric acid) | - |
Bos taurus | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.6.1.18 | Bos taurus | P61823 | - |
- |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 4.6.1.18 | poly (C) + H2O | - |
Bos taurus | 3'-CMP + 3'-phosphooligonucleotides | - |
? | |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 4.6.1.18 | 0.000000011 | - |
oligo(vinylsulfonic acid) | without NaCl | Bos taurus | |
| 4.6.1.18 | 0.0004 | - |
oligo(vinylsulfonic acid) | pH 6.0, 0.1 M NaCl | Bos taurus | |
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Release 2023.1 (January 2023)
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